🏥 Quality Health Care
PATIENT INFORMATION LEAFLET: INFORMATION FOR THE USER
Capsules:
Each capsule contains:
- Ampicillin Trihydrate (equivalent to 250 mg Ampicillin)
- Cloxacillin Sodium (equivalent to 250 mg Cloxacillin)
Suspension (5 ml reconstituted):
- Ampicillin Trihydrate (equivalent to 125 mg Ampicillin)
- Cloxacillin Sodium (equivalent to 125 mg Cloxacillin)
📘 Read Carefully Before Use
- Keep this leaflet. You may need to refer to it again.
- If you have questions, consult your doctor, healthcare provider, or pharmacist.
- Do not share this medicine with others—it may harm them.
- Report any serious or unexpected side effects to your healthcare provider.
📑 Contents of This Leaflet
- What Amciclox is and what it is used for
- What you should know before taking Amciclox
- How to take Amciclox
- Possible side effects
- How to store Amciclox
- Further information
1️⃣ What Amciclox Is and What It Is Used For
Amciclox combines two antibiotics:
- Ampicillin: A broad-spectrum penicillin effective against various bacterial infections.
- Cloxacillin: Targets and kills susceptible bacteria.
Indications include:
- Ear, nose, and throat infections
- Bronchitis, pneumonia
- Urinary tract infections
- Gonorrhoea, gynaecological infections
- Septicaemia, peritonitis, endocarditis
- Meningitis, enteric fever, gastrointestinal infections
⚠️ Only use under a doctor’s prescription.
2️⃣ What You Should Know Before Taking Amciclox
❌ Do Not Take If:
- You're allergic to Ampicillin, Cloxacillin, or any ingredients in Amciclox
- You've had skin rash or swelling from antibiotics
- You have infectious mononucleosis, lymphatic leukemia, or are on allopurinol (risk of skin rash)
⚠️ Take Special Care If:
- You’ve had serious reactions to antibiotics
- You have liver, kidney issues, gout, or syphilis
- You're pregnant, breastfeeding, or over 50
- You're on a low sodium diet
- You're undergoing urine glucose tests (may show false positives)
💊 Drug Interactions:
- Avoid with: Aminoglycosides, tetracyclines, erythromycin, polymyxin B
- May interact with: Chloramphenicol, Probenecid, Methotrexate, Warfarin
- May affect absorption of other medicines due to changes in gut flora
🍽️ Food & Drink:
- Take 30 minutes to 1 hour before meals
- Avoid alcohol
🤰 Pregnancy & Breastfeeding:
- Consult your doctor before use
- Trace amounts may pass into breast milk
🚗 Driving & Machinery:
- No known effects, but avoid machinery if drowsy
🧂 Ingredients Note:
- Suspension contains sodium methyl and propyl parabens (Nipagin/Nipasol blend)
- Discuss allergies or sensitivities with your doctor
3️⃣ How to Take Amciclox
Always follow your doctor’s instructions. Take on an empty stomach (30 mins to 1 hour before meals or 2 hours after).
💊 Dosage Guidelines:
| Age Group | Dosage |
|---|---|
| Adults & >10 years | 1–2 capsules every 6 hours |
| Children 2–10 years | 5–10 mL suspension every 6 hrs |
| Children <2 years | 2.5–5 mL suspension every 6 hrs |
Reconstitution:
To prepare 100 ml suspension, add 85 ml water, invert bottle, and shake well.
🚨 Overdose:
- Symptoms: Rapid onset of side effects, convulsions, CNS toxicity
- Seek immediate medical help
- Treatment: Adrenaline, corticosteroids, antihistamines; supportive care
⏰ Missed Dose:
- Take as soon as remembered unless close to next dose
- Do not double dose
4️⃣ Possible Side Effects
⚠️ Common:
- Diarrhoea, indigestion, nausea, vomiting
- Mild allergic reactions (rash, itching)
🚨 Severe (Rare):
- Swollen face, breathing difficulty
- Blistering rash, skin peeling, fever
- Blisters in mouth, throat, eyes, anus, genitals
🩺 Report Immediately If You Notice:
- Liver issues: nausea, vomiting, jaundice, dark urine
- Severe diarrhoea with cramps
- Kidney problems: painful/bloody urination
- Blood disorders: frequent infections, bleeding, bruising
- Anaemia symptoms: fatigue, breathlessness, yellowing of skin
- Muscle aches, joint pain, fever
- Black “hairy” tongue (harmless, resolves post-treatment)
5️⃣ How to Store Amciclox
- Store in a cool, dry place
- Keep out of reach of children
- Use suspension within the recommended period after reconstitution
6️⃣ Further Information
For full ingredient list and additional details, consult your doctor or pharmacist.
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the FDA through the Med Safety App. Download the App on Google play store or apple store.