Ciprofloxacin Injection USP 200 mg/10Oml

For the use of Registered Medical Practitioner or Hospital or Laboratory

Composition:

Each 1 00 ml contains:

Ciproiloxacin 200 mg

Sodiunm Chloride USP USP 0.9% w/v

Water for Injection USP q.S.

DESCRIPTION: Ciprofloxacin Injection USP is a synthetic broad spectrum-antimicrobial agent for intravenous ((V) administration. Ciprofloxacin is one of the most active fluorinated quinolones.

MODE OF ACTION: Ciprofloxacin is bactericidal and acts by inhibiting the subunit A of DNA gyrase (topoisomerase) which is essential for reproduction of bacterial DNA.

INDICATIONS: Ciprofloxacin Injection USP is indicated for the treatment of a wide variety of infections caused by susceptible strains of gram-positive and gram-negative organisms including mixed infections caused by two or more organisms.

Ciprofloxacin Injection USP is indicated for the treatment of the following infections caused by susceptible bacteria:

Respiratory tract infections bronchopneumonia, acute exacerbation of chronic bronchitis and Jung infections in patients with Cystic fibrosis, Urinary tract infections, chronic bacterial prostatitis; skin and skin structure infections; and bacterial gastrointestinal infection.

DOSAGE: As directed by the Physician.

FOR INTRAVENOUS USE ONLY.

• Use only if the solution is clear and free from visible particles and if the container is undamaged.
• Discard any remaining solution immediately after use.

SIDE EFFECTS: Ciprofloxacin Injection USP is generally well tolerated Common side effects include nausea, vomiting, diarrhea, stomach pain, headache, restlessness, skin rash and convulsions etc.

CONTRA-INDICATIONS: Ciprofloxacin Injection USP is Contra-indicated in persons with history of hypersensitivity to Ciprofloxacin or any member of the quinolone class of antimicrobial agents.

PRECAUTIONS: Ciprofloxacin Injection USP should be administered by slow injection over a period of 60 minutes. Local 1.V. site reactions have been reported with the intravenous administration of Ciprofloxacin. These reactions are more frequent if injection time is 30 minutes or less or if small veins of the hand are used.

WARNINGS: Ciprofloxacin Injection USP should be used with caution in patients with epilepsy or a history of CNS disorders.

Care is necessary in patients with impaired hepatic or renal function, G6PD deficiency, or myasthenia gravis. Adequate fluid intake should be maintained during treatment with ciprofloxacin and excessive alkalinity of the urine avoided because of the risk of crystalluria.

DRUG INTERACTIONS: Fluoroquinolones are known to inhibit hepatic drug metabolism and may interfere Nith the learance of drugs, such as theophylline, that are metabolized by the liver. Cations such as aluminum, magnesium, or iron reduce the absorption of ciprofloxacin and related drugs when given concomitantly.

STORAGE: Store in a cool, dry & dark place. Do not freeze.

Keep all medicines out of reach of children.

PRESENTATION: 100 ml of LDPE Container.

Manufactured by:

Axa Parenterals Lid

36, 937 & 939, Village-Kishanpur,

aalpur Roorkee,

PHstal code-247667 (Uttarakhand), India.