HYDROCORTISONE SODIUM SUCCINATE INJECTION
For I.M./I.V. Injection
100MG
It acts rapidly but has short duration of action. In addition to primary glucocorticoid, it has significant mineralocorticoid activity also. Hydrocort. Sod Succ. Inj. supplements the action of adrenaline or when adrenocortical function has been suppressed by prolonged corticosteroid therapy.
INDICATION:
Status asthmaticus and acute allergic reaction, in anaphylatic reaction to drugs. Severe shock (surgical, accidental trauma or overwhelming infection). Addison's disease, Simmond's disease, tuberculous meningitis & other meningitis.
DOSAGE:
100–500 mg admin. by slow I.V. 3–4 time a day. Systemic therapy in children: up to 1 yrs: 25 mg, 1–5 yrs: 50 mg, 6–12 yrs: 100 mg.
CONTRA-INDICATIONS:
Systemic infection, unless specific anti-infective therapy is employed. Live virus immunization. Hypersensitivity should not be injected directly into tendons.
SPECIAL PRECAUTIONS:
Impair the ability to resist & counteract infection, pregnancy. May reduce the effects of anticholinesterases in myasthenia gravis, cholecystographic X-ray media & salicylates.
SIDE EFFECT:
Peptic ulceration or may be aggravated, Hypercorticism.
DRUG INTERATION:
Reduced efficacy with concurrent use of carbamazepine, phenytoin, primidone and barbiturates. Rifampicin reduces corticosteroid activity, peptic ulcer with concurrent NSAID'S administration. Dose of antidiabetics and antihypertensives needs to be increased. Decreases serum concentration of salicylates and antimuscarinic agents.
STORAGE:
Protect from light. Store below 25°C in a dry place.
EXPIRY:
Three years.